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ÇØ¿ÜÁÖ¹® [POD] Making Sense of Life Explaining Biological Development with Models, Metaphors, and Machines

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Evelyn Fox Keller ÁöÀ½ | Harvard University Press | 2003³â 10¿ù 31ÀÏ
Making Sense of Life
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ISBN 9780674012509(067401250X)
Âʼö 388ÂÊ
¾ð¾î English
Å©±â 133(W) X 215(H) X 27(T) (mm)
Á¦º»ÇüÅ Paperback
»ðÈ­À¯¹« »ðÈ­ÀÖÀ½
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What do biologists want? If, unlike their counterparts in physics, biologists are generally wary of a grand, overarching theory, at what kinds of explanation do biologists aim? How will we know when we have "made sense" of life? Such questions, Evelyn Fox Keller suggests, offer no simple answers. Explanations in the biological sciences are typically provisional and partial, judged by criteria as heterogeneous as their subject matter. It is Keller's aim in this bold and challenging book to account for this epistemological diversity--particularly in the discipline of developmental biology. In particular, Keller asks, what counts as an "explanation" of biological development in individual organisms? Her inquiry ranges from physical and mathematical models to more familiar explanatory metaphors to the dramatic contributions of recent technological developments, especially in imaging, recombinant DNA, and computer modeling and simulations. A history of the diverse and changing nature of biological explanation in a particularly charged field, Making Sense of Life draws our attention to the temporal, disciplinary, and cultural components of what biologists mean, and what they understand, when they propose to explain life.
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Prefacep. vii
Introductionp. 1
Models: Explaining Development without the Help of Genesp. 11
Synthetic Biology and the Origin of Living Formp. 15
Morphology as a Science of Mechanical Forcesp. 50
Untimely Births of a Mathematical Biologyp. 79
Metaphors: Genes and Developmental Narrativesp. 113
Genes, Gene Action, and Genetic Programsp. 123
Taming the Cybernetic Metaphorp. 148
Positioning Positional Informationp. 173
Machines: Understanding Development with Computers, Recombinant DNA, and Molecular Imagingp. 199
The Visual Culture of Molecular Embryologyp. 205
New Roles for Mathematical and Computational Modelingp. 234
Synthetic Biology Redux--Computer Simulation and Artificial Lifep. 265
Conclusion: Understanding Developmentp. 295
Notesp. 305
Referencesp. 351
Indexp. 382
Table of Contents provided by Ingram. All Rights Reserved.

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